Letter to the editor
Clinical and Epidemiological Characteristics of Patients Diagnosed
with COVID-19 in a Tertiary Care Center in Mexico City: A Prospective Cohort
Study
Carlos E. Mendez-Probst1
*
David Velazquez-Fernandez2
Ricardo Castillejos-Molina1
1Department of Urology and Instituto Nacional de
Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
2Surgery Division, Instituto Nacional de
Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico
Dear Editor:
We have read the paper entitled “Clinical and Epidemiological Characteristics of Patients
Diagnosed with COVID-19 in a Tertiary Care Center in Mexico City: A Prospective Cohort
Study” by Ortiz-Brizuela and colleagues1, in the
May-June issue of the Revista de Investigacion Clínica-Clinical and Translational
Research, we would to make out some observations on the reported data.
According to table 1 of the article, if the number of obese subjects in the entire cohort
is 67 out of 309 subjects, then the percentage of obesity is 21.6%, and not 39.6% as
stated, the same would apply to overweight subjects (21.6%). Furthermore, in the
inpatient cohort, the percentage of obese/overweight subjects is once again overstated
as 39.7% and 41.3% (n = 50/52 out of 140), respectively, using these number the
percentages would correspond to slightly lower figures (35.7% and 37.1%). Finally, in
the outpatient cohort, the reported subjects with obesity/overweight are 39.5% and
34.9%, but with 17 and 15 subjects out of 169 individuals, the percentages should be far
lower at 10% and 8.8%, respectively.
Thus, the paper’s conclusion that patients with COVID-19 diagnosis were obese or
overweight is quite ambiguous and irrelevant as most of the cohort is not comprised by
subjects with excessive weight (overweight or obese).
REFERENCES
1. Ortiz-Brizuela E, Villanueva-Reza, González-Lara MF, Tamez-Torres
KM, Román-Montes CM, Díaz-Mejía BA, et al. Clinical and epidemiological
characteristics of patients diagnosed with COVID-19 in a tertiary care center in
mexico city:a prospective cohort study. Rev Invest Clin.
2020;72:165-77.
[ Links ]
We appreciate the interest of Mendez-Probst and colleagues on our results recently
published in Revista de Investigación Clínica – Clinical and Translational
Investigation1. Although most relevant
data in the study were prospectively collected, some information also was obtained
from medical records. Hence, the possibility of missing data is a weakness of our
study. Most of the missing information in table 1 concerns to the outpatient’s group
who were evaluated once in a triage room. Note that the number of valid observations
for each binary variable can be easily deduced from the table using simple
arithmetic operations (with the percentage and number of observations reported). For
example, as stated in table 1, dysgeusia was reported in 100% of outpatients,
nevertheless, only one subject reported this symptom. Consequently, it can be easily
inferred that this symptom was only assessed in one patient. However, considering
Mendez-Probst et al. observation to interpret table 1, we provide new tables 1-3 in
the Corrigendum section of this issue, detailing the number of valid observations
for each variable. Moreover, we understand Mendez-Probst et al. concerns regarding
the validity of the comparison between inpatients and outpatients due to amount of
missing data. Consequently, we updated this comparison with our data recollected up
to June 1, and similar findings were found: a prevalence of overweight or obesity in
83% (671/808) and 49.4% (267/540), among inpatients and outpatients, respectively (p
< 0.01) (unpublished data).
Copyright: © 2020 Revista de Investigación
Clínica.