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Revista de investigación clínica

versión On-line ISSN 2564-8896versión impresa ISSN 0034-8376

Rev. invest. clín. vol.72 no.6 Ciudad de México nov./dic. 2020  Epub 09-Abr-2021

https://doi.org/10.24875/ric.20000194 

Letter to the editor

Echinococcus Granulosus Haplotypes in the Scientific Literature

Armando Totomoch-Serra1  2  * 

Nayely García-Méndez1 

Carlos Manterola1  3  4 

1PhD Program in Medical Sciences, Universidad de La Frontera, Temuco, Chile

2Department of Genetics and Molecular Biology, Center for Research and Advanced Studies, Instituto Politécnico Nacional, Mexico City, Mexico

3Center for Excellence in Morphological and Surgical Studies (CEMyQ), Universidad de La Frontera, Temuco, Chile

4Department of Surgery, Universidad de La Frontera, Temuco, Chile


Dear Editor

Echinococcus granulosus (Eg) is a parasite causing an incidental infection in humans. The disease can be observed as a hydatid cyst in the liver and lungs and is found in dogs and wolves as definitive hosts. It is considered a neglected infectious disease which has rarely been studied in Mexico1. In several studies worldwide, the genetic study of mitochondrial DNA (mtDNA) sequencing of cox1 and nad1 partial sequences is predominant. However, studies of haplotypes obtained or concatenated (analysis combining sequences of two or more genes) are scarce.

The research group in Medical Science of the Universidad de La Frontera, located in the Araucania Region in Chile where Eg is endemic, recently created a study group to analyze this disease from the clinical and basic sciences viewpoint. Consequently, during different studies performed, the group has identified the various haplotypes informed in the literature and is interested in contributing and sharing with the scientific community, the information collected and classified according to the main characteristics of the disease.

Eg has high genetic variability and the classification applied in different studies is diverse. In reference to the different populations informed, the analysis of haplotypes can help to trace changes in the evolutive forces, to perform in phylogeography analysis and to determine the global genetic structure2,3. By having the information available, the researchers performing mtDNA haplotype analysis can easily access published data to compare and design their haplotype analysis. The information may be accessed as supplementary material (Supplementary Table 1).

SUPPLEMENTARY DATA

Supplementary data are available at Revista de Investigación Clínica online (www.clinicalandtranslationalinvestigation.com). These data are provided by the corresponding author and published online for the benefit of the reader. The contents of supplementary data are the sole responsibility of the authors.

SUPPLEMENTARY MATERIAL

REFERENCES

1. Totomoch-Serra A, Manterola C. Importance of genotyping cystic echinococcosis in humans from Mexico. Arch Med Res. 2020;51:63-4. [ Links ]

2. Ito A, Yanagida T, Nakao M. Recent advances and perspectives in molecular epidemiology of Taenia solium cysticercosis. Infect Genet Evol. 2016;40:357-67. [ Links ]

3. Spotin A, Boufana B, Ahmadpour E, Casulli A, Mahami-Oskouei M, Rouhani S, Assessment of the global pattern of genetic diversity in Echinococcus multilocularis inferred by mitochondrial DNA sequences. Vet Parasitol. 2018;262:30-41. [ Links ]

Received: April 29, 2020; Accepted: May 07, 2020

* Corresponding author: Armando Totomoch-Serra E-mail: totomoch@gmail.com

Creative Commons License Instituto Nacional de Cardiología Ignacio Chávez. Published by Permanyer. This is an open ccess article under the CC BY-NC-ND license