JIMENEZ-ARELLANES, María Adelina et al. Actividad antimicobacteriana y antiprotozoaria de Moussonia deppeana (Schldl and Cham) Hanst. []. , 44, 2, pp.31-35. ISSN 1870-0195.

^les^aMoussonia deppeana es conocida como tlachichinole, clachichinole, etc. En la medicina tradicional de México se utiliza para tratar: padecimientos gastrointestinales, tos, úlceras estomacales y/o duodenales, infecciones renales y vaginales. Los extractos orgánicos fueron evaluados contra once cepas de micobacterias y tres parásitos. El extracto AcOEt resultó activo contra Mycobacterium tuberculosis H37Rv, H37Rv resistente a etambutol y contra el aislado clínico SIN4 (CMI = 12.5 μg/mL), contra MMDO mostró una CMI=25 μg/mL. El extracto Hex resultó moderadamente activo contra H37Rv resistente a etambutol y contra los aislados clínicos SIN4 y MMDO (CMI=25 μg/mL). Los extractos de Hex, AcOEt y EtOH resultaron inactivos contras las micobacterias no tuberculosas (CMI > 50 μg/mL) y contra Giardia lamblia, Entamoeba histolytica y Trichomona vaginalis mostrando IC₅₀ >200 μg/mL. M. deppeana biosintetiza compuestos con actividad antimicobacteriana.^len^aMoussonia deppeana is known as tlachichinole, clachichinole, etc. In Mexican traditional medicine is used to treat gastrointestinal disorders, cough, stomach and duodenal ulcers, kidney and vaginal infections. The organic extracts prepared by maceration were evaluated against 11 mycobacterial strains and three protozoal. The AcOEt extract was active against Mycobacterium tuberculosis H37Rv, etambutol-resistant of H37Rv, and the clinical isolate SIN4 showed MIC=12.5 μg/mL, and against MMDO showed an MIC = 25 μg/mL. The Hex extract resulted moderately active against ethambutol-resistant of H37Rv and clinical isolates SIN4 and MMDO (MIC = 25 μg/mL). The Hex, AcOEt, and EtOH extracts were inactive against non-tuberculous mycobacterium strains showed MIC >50 μg/mL and against Giardia lamblia, Entamoeba histolytica, and Trichomona vaginalis showed IC₅₀ >200 μg/mL. M. deppeana biosynthesized compounds with antimycobacterial activity.

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