Abstract

URIARTE-DUQUE, Juan  and  HERNANDEZ-RIVERA, Gabriela. Treatment of non-Hodgkin's lymphoma associated with acquired immunodeficiency syndrome (AIDS) at the Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán. Gac. Méd. Méx [online]. 2006, vol.142, n.2, pp.99-102. ISSN 2696-1288.

Background: Survival in patients with acquired immunodeficiency syndrome (AIDS) related non-Hodgkin 's Lymphoma has improved with the use of High Active Antiretroviral Therapy (HAART) and less toxic chemotherapy. Material and methods: Clinical characteristics and outcome among patients treated for AIDS related non-Hodgkin's Lymphoma are described. Nine patients were studied retrospectively. Overall survival (OS) and Free Disease Survival (FDS) using a Kaplan-Meier model were analyzed. Results: Patients received (DA-EPOCH) etoposide, prednisone, vincristine, doxorubicin and cyclophosphamide. The overall Survival was 18 months and 13 month Free Disease Survival with a median follow-up of 16 months showing full response in 8/9 patients was observed. Conclusions: A very satisfactory treatment response in this group of patients expressed as an increased Overall Survival was noted.

Keywords : AIDS; non-Hodgkin's lymphoma; antiretroviral treatment; EPOCH.