Abstract

CEBALLOS-GONZALEZ, Sergio et al. Comparative effectiveness between 0.1% metilprednisolone aceponate and 0.05% betamethasone dipropionate among children with nonretractable prepuce. Gac. Méd. Méx [online]. 2006, vol.142, n.2, pp.121-124. ISSN 2696-1288.

Objective: To compare clinical improvement between treatment with metilprednisolone aceponate vs. betamethasone dipropionate among children with nonretractable prepuce. Material and methods: Between August 2001 and November 2002, we carried out a double blind and controlled clinical trial in 34 children with a diagnosis of nonretracable prepuce. Children were randomly assigned to one of the following groups and topical treatment was administered: Group A; metilprednisolone aceponate 0.1% and Group B; betamethasone dipropionate 0.05%. Results: Improvement was noted in 88.2% of our sample studied; (n=15) children from group A and 76.4% (n=13) children from group B; however, we did not observe a significant difference when comparing percentages between the two groups ( = 0.2; p = 0.6). Conclusions: The percentage of clinical improvement was similar between the two groups of topical steroid treatment administered.

Keywords : Metilprednisolone aceponate; betamethasone dipropionate; children; nonretractable prepuce.