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Gaceta médica de México
On-line version ISSN 2696-1288Print version ISSN 0016-3813
Abstract
RAMIREZ-STIEBEN, Luis A. et al. 25(OH)D levels during the COVID-19 pandemic: impact of lockdown and ultraviolet radiation. Gac. Méd. Méx [online]. 2023, vol.159, n.3, pp.190-198. Epub June 12, 2023. ISSN 2696-1288. https://doi.org/10.24875/gmm.m23000747.
Background:
Home confinement policies during the COVID-19 pandemic limited sun exposure and may have influenced on vitamin D levels.
Objective:
To assess changes in 25(OH)D during the COVID-19 pandemic and the impact of Mandatory Preventive Social Isolation (MPSI) on UV radiation recommended dose modified by clouds for the synthesis of vitamin D (UVDVC).
Material and methods:
A retrospective study was carried out on 15,908 patients in whom the level of 25(OH)D was determined between January 2019 and December 2021 in a centralized laboratory in Rosario, Argentina.
Results:
Lower levels of 25(OH)D were documented in people younger than 40 years during 2020, as well as a variation during the pandemic period, with lower values in the first wave. Lower levels of 25(OH)D were recorded in the post-MPSI period in comparison with the MPSI period (p < 0.00001), in addition to a higher frequency of hypovitaminosis D (48.6% vs. 36.1%). These differences were not observed in the comparison of the same periods of 2019. UVDVC did not vary between 2019 and 2020.
Conclusions:
The restrictions due to the COVID-19 pandemic led to a higher frequency of hypovitaminosis D and lower frequency of optimal values.
Keywords : COVID-19; Quarantine; Vitamin D deficiency.