Abstract

GARCIA-SAENZ, Manuel  and  ESPINOSA-CARDENAS, Etual. Amiodarone-induced thyrotoxicosis (TIA): a diagnostic and therapeutic challenge. Rev. Fac. Med. (Méx.) [online]. 2018, vol.61, n.5, pp.24-29. ISSN 2448-4865.

Amiodarone induced thyrotoxicosis (AIT) appears on the 5-12% of patients, it potentially can exacerbate a cardiac illness, leading to an increase in the morbility/mortality of patients. Two types of AIT exist, each one with a different etiology. It is important to distinguish between them to be able to establish a treatment. However, sometimes it can be quite difficult.

Case Report: An 81 year-old woman, with a history of acute myelod leukemia, showed up with thyroid enlargement at the ER. She was discharged 48 h earlier, after an atrial fibrillation (AF) episode which was controlled with amiodarone IV infusion. Because the biochemical diagnosis of thyrotoxicosis and reaparition of AF,an AIT was suspected.

To be able of distinguishing between the two types of AIT is essential to establish a treatment. The use of a thyroid doppler sonography and a thyroid scintigraphy is helpful. The comorbidities of the patient and the possible side effects should be taken into account when deciding the treatment.

Keywords : Thyrotoxicosis; amiodarone; thyroiditis.