Abstract

MARTELL GONZALEZ, Mario Roberto  and  CUEVAS BAILON, Mario Axel. Radiological Diagnosis of Pituitary Stalk Disruption Syndrome. Ectopic Neurohypophysis. Rev. Fac. Med. (Méx.) [online]. 2021, vol.64, n.1, pp.32-36.  Epub July 06, 2021. ISSN 2448-4865.  https://doi.org/10.22201/fm.24484865e.2021.64.1.05.

Pituitary stalk disruption syndrome is a congenital anomaly characterized by neuroradiologic demonstration of an absent, interrupted, or hypoplastic pituitary stalk, aplastic/ hypoplastic adenohypophysis, and ectopic neurohypophysis. This syndrome has been related to severe forms of congenital hypopituitarism, associated with multiple deficiencies of pituitary hormones. Perinatal signs and symptoms presented by patients include hypoglycemia in up to 61%, jaundice in 38%, micropenis in 77% and cholestasis in 19%, neonatal seizures occurred in 75% of children. During childhood, they tend to have short stature and a decrease in growth speed, as well as a delay in the expression of secondary sexual characteristics.

In our clinical case, an adolescent patient was presented whose main clinical manifestations were delayed secondary sexual characteristics, the main findings were found in nuclear magnetic resonance, including absence of the pituitary stalk, ectopic neurohypophysis, located adjacent to the tuber cinereum and hypoplastic adenohypophys.

Keywords : Sella turcica; pituitary stalk; neurohypophysis; adenohypophysis; hyperintense; magnetic resonance imaging.