Abstract

CHAVIRA ANAYA, Cynthia Fabiola; ARRIAGA LOPEZ, Alberto  and  ALVAREZ TORRES, Alfredo. Von Willebrand's Disease as a Risk Factor for Postpartum Hemorrhage. Case Report. Rev. Fac. Med. (Méx.) [online]. 2021, vol.64, n.2, pp.31-37.  Epub July 06, 2021. ISSN 2448-4865.  https://doi.org/10.22201/fm.24484865e.2021.64.2.05.

The Von Willebrand´s disease is the most common inherited bleeding disorder, with higher prevalence in women in fertile age. There are three principle types, that are caused by either a quantitative or qualitative defect in von Willebrand factor and in severe cases, the coagulation factor VIII is affected too. The incidence in pregnancy is relatively infrequent, however there are worldwide reports where it has been considered a risk factor for bleeding during the resolution of pregnancy. We present the case of a 20-year-old woman on her second pregnancy, with a previous abortion, who had a full-term pregnancy with a diagnosis of Von Willebrand disease since she was twelve years old, treated with nasal desmopressin only in the presence of hemorrhagic events. Gestation was terminated via abdominal route due to failed induction, and in spite of preoperative hematologic and anesthetic prophylactic management, she presented postpartum hemorrhage, according to current definitions based on national and international guidelines, attributing the cause of the bleeding to the patient's coagulopathy.

Keywords : Von Willebrand´s disease; pregnancy; postpartum hemorrhage.