Abstract

MEZA-SANCHEZ, David E.  and  MARAVILLAS-MONTERO, José L.. Clinical and Biomedical Applications of Surface Plasmon Resonance Systems. Rev. invest. clín. [online]. 2019, vol.71, n.2, pp.85-90.  Epub Apr 12, 2021. ISSN 2564-8896.  https://doi.org/10.24875/ric.18002754.

Surface plasmon resonance (SPR)-based biosensors offer superior analytical features such as simplicity, sensitivity, and specificity when compared to conventional methods in clinical analyses. In addition, they deliver real-time monitoring of label-free analytes with high-throughput approaches requiring little sample pretreatment that allows the analysis of virtually every clinical sample type to determine the amount and/or activity of any molecule of interest. Accordingly, SPR emerges as a novel, efficient, powerful, and relatively low-cost alternative tool for routine clinical analysis, opening also new horizons for developments in personalized medicine applied to diagnostics or therapeutics’ monitoring.

Keywords : Surface plasmon resonance; Biomarker; Clinical diagnostics.

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