Objective:

We describe two adolescent patients with multiple sclerosis, which is a demyelinating disease of the central nervous system. Presentation of the cases: The first case was a 14-year-old female patient with overweight; her condition was characterized by dizziness, headache, paresthesia in the lower limbs, diplopia and bradylalia. On physical examination, compatible data of cerebellar involvement were identified. A magnetic resonance imaging (MRI) of the skull showed areas of demyelination in the posterior fossa. Multiple sclerosis, the relapsing-remitting variety, is diagnosed. After the administration of steroids and beta interferon, there was improvement in symptoms. Second case: 13-year-old female, who presented fall from her own height, bladder incontinence, loss of strength in the left arm and leg. On physical examination, left hemiparesis was detected. MRI: demyelination data in lateral ventricle, cerebellum and spinal cord. The patient improved after starting steroids and interferon.

Conclusions:

The clinical presentation of multiple sclerosis in pediatric patients is a challenge, since it is a condition with unspecific manifestations. Establishing the diagnosis requires multiple studies. The earlier treatment is started, the more favorable the prognosis.