Introduction:

Guillain-Barré syndrome (GBS) is an acute inflammatory demyelinating polyradiculoneuropathy characterized by flaccid, areflexic, ascending and symmetrical paralysis, which may have an infectious origin. It has recently been associated with COVID-19.

Case presentation:

Two pediatric patients with GBS and in whom COVID-19 was diagnosed by PCR are described. In both patients, the diagnosis of GBS was confirmed by neuroconduction studies. Both received treatment with immunoglobulin and had complete resolution of the neurological symptoms.

Conclusions:

Given that GBS can occur in pediatric patients with COVID-19, both conditions should be suspected in patients with clinical data similar to the cases reported here.