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Salud Pública de México
Print version ISSN 0036-3634
Abstract
HURTADO-SALGADO, Erika et al. Use of HPV testing in cervical cancer screening services in Mexico, 2008-2018: a nationwide database study. Salud pública Méx [online]. 2018, vol.60, n.6, pp.722-733. Epub Aug 22, 2019. ISSN 0036-3634. https://doi.org/10.21149/9891.
Objective:
To describe the methods of a study aimed at evaluating high risk-HPV (hrHPV)-based screening and cervical cytology as triage compared to conventional cervical cytology as primary screening in the detection of grade 2+ cervical intraepithelial neoplasia in the National Cancer Screening Program (NCSP) of Mexico.
Materials and methods:
We will use information originated from the Womens Cancer Information System of Mexico regarding cervical cancer from 2008 to 2018. The database includes cytology results, diagnostic confirmation by histopathology and/or treatment colposcopy. We will then carry out statistical analyses on approximately 15 million hrHPV.
Results:
We will evaluate the overall performance of hrHPV-based screening as part of the NCSP and compare hrHPV-based to cytology-based screening under real-life conditions. To guarantee an unbiased comparison between hrHPV with cytology triage and conventional cytology we will use propensity score matching.
Conclusion:
Decision makers may use our results to identify areas of opportunity for improvement in NCSP processes.
Keywords : cervical intraepithelial neoplasia; cervical smears; DNA probes, HPV; health informations systems; Mexico.
