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Salud Pública de México
Print version ISSN 0036-3634
Abstract
RICHARDSON-LOPEZ COLLADA, Vesta; BAUTISTA-MARQUEZ, Aurora; SANCHEZ-URIBE, Edgar and ESPARZA-AGUILAR, Marcelino. Population impact of rotavirus vaccination in Mexico after 10 years. Salud pública Méx [online]. 2020, vol.62, n.1, pp.6-13. Epub Feb 28, 2022. ISSN 0036-3634. https://doi.org/10.21149/9936.
Objective:
To evaluate the impact of rotavirus (RV) vaccination after 10 years of it´s universalization on morbidity and mortality from Acute Diarrheal Disease (ADD) in mexican children under five years of age.
Materials and methods:
Annual median numbers for ADD new cases, hospitalizations and deaths were compared between pre and post universalization periods; absolute and relative reductions were calculated, considering p<0.05 values as significant.
Results:
Mortality, hospitalizations and new cases from ADD in children under five decreased 52.6, 46, and 15.5% respectively, in the posuniversalization period. During rotavirus seasons, reduction in mortality, hospitalizations and new cases was 66.9, 64.7, and 28.7% respectively.
Conclusions:
As of the universal introduction of RV vaccination in Mexico, significant and sustained reductions are appreciated for mortality and hospitalizations from ADD, less so for incidence. A most prominent effect is observed during the winter season.
Keywords : rotavirus vaccines; impact; mortality; hospitalizations; diarrhea.