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Salud Pública de México

Print version ISSN 0036-3634

Abstract

SALAZAR-MARTINEZ, Eduardo et al. Markers of kidney function among SARS-CoV-2 infected patients. A rapid review of the literature. Salud pública Méx [online]. 2021, vol.63, n.2, pp.253-261.  Epub Feb 27, 2023. ISSN 0036-3634.  https://doi.org/10.21149/11918.

Objective:

To summarize the scientific literature on kidney abnormalities associated with SARS-CoV-2 infection.

Materials and methods:

It was conducted a rapid review using the Cochrane methodology.

Results:

Pre-existing chronic kidney disease (CKD) in SARS-CoV-2 infected patients ranged from 1-38% and acute kidney injury (AKI) ranged from 2.9-86.4%. The prognosis of patients with SARS-CoV-2 infection was worse among those with CKD and those with normal remnant kidney function (RKF) that developed AKI. The risk of death was higher (pooled risk ratio =1.49; 95%CI: 1.09-2.04) among SARS-CoV-2 infected patients with pre-existing CKD. The RKF markers showed alterations among severe and non-surviving SARS-CoV-2 patients; the most common marker was serum creatinine.

Conclusions:

The scientific evidence shows the relevance of the evaluation and permanent monitoring of the RKF in SARS-CoV-2 hospitalized patients to improve the prognosis of those with pre-existing CKD as well as the prognosis of those without CKD who develop AKI.

Keywords : SARS-CoV-2; chronic kidney disease; acute kidney injury; comorbidity; renal biomarkers.

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