Objective:

To describe the design and field results of the National Health and Nutrition Survey (Ensanut, for its Spanish acronym) Covid-19.

Materials and methods:

Ensanut Covid-19 is a probabilistic household survey. The following elements of the design are described in this article: scope, sampling, measurement, inference, and logistic organization.

Results:

Ensanut, Covid-19 got 10 216 completed household interviews and 9 464 individual results on SARS-CoV-2 seropositivity. The household response rate was 80%. The response rate to the seropositivity test was 44%.

Conclusions:

The probabilistic design of Ensanut Covid-19 allows to make valid statistical inferences on parameters of interest to public health at the national and regional levels. In particular, Ensanut, Covid-19 will enable to make inferences of practical utility on the prevalence of seropositivity to SARS-CoV-2 in Mexico. In addition, Ensanut Covid-19 2020 can be compared to previous Ensanut, in order to identify potential changes in the health and nutrition status of the Mexican population.