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Salud Pública de México

Print version ISSN 0036-3634

Abstract

JUAREZ-PEREZ, Cuauhtémoc Arturo et al. Neurotoxicity among petrochemical workers with low exposure indexes to organic solvents. Salud pública Méx [online]. 2022, vol.64, n.3, pp.290-298.  Epub Oct 30, 2023. ISSN 0036-3634.  https://doi.org/10.21149/12916.

Objective:

To estimate the neuropsychological performance and its association with exposure to organic solvents (OS) among petrochemical workers in Mexico.

Materials and methods:

Cross-sectional study including 203 workers: 102 exposed to OS and 101 non-exposed. Neuropsychological performance was evaluated with Neurobehavioral Core Test Battery. Exposure to OS was evaluated with the metabolites from exposure to toluene, xylenes and benzene.

Results:

Exposed workers presented with a worse performance in all tests (p<0.05), except for Santa Ana test. This was corroborated with regression models; workers exposed to OS had a higher number of mistakes and performed the tests in longer time (p<0.05), together with having greater odds of neurotoxicity symptoms (OR: 2.93; 95%CI: 0.96, 8.96).

Conclusions:

Occupational exposure to organic solvents, even at levels allowed by current Mexican standards, was related to an impaired neuropsychological performance.

Keywords : toluene; organic solvents; toxicity; neurology; occupational exposure.

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