Introduction:

The hemolytic uremic syndrome in its atypical variety is a rare thrombotic microangiopathy, with high morbidity and mortality if a timely diagnosis is not available to allow an adequate specific treatment.

Clinical case:

Patient with a confirmed diagnosis of atypical hemolytic uremic syndrome treated with eculizumab with total remission and satisfactory clinical evolution. Diagnostic suspicion is important for early and specific treatment and favorable prognosis.

Conclusion:

The case reported here is illustrative of the clinical presentation of the atypical haemolytic uraemic syndrome. Its evolution was torpid, despite the treatment with plasma infusion and plasmapheresis and its total remission with eculizumab. In Mexico, few cases have been confirmed, only in some cases has the specific treatment been administered.