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Medicina interna de México

Print version ISSN 0186-4866

Abstract

ZAMORA-CERVANTES, Laura Elena et al. The neutrophil/lymphocyte index as a predictor of morbidity and mortality in pneumonia due to influenza. Med. interna Méx. [online]. 2019, vol.35, n.3, pp.349-354.  Epub Mar 05, 2021. ISSN 0186-4866.  https://doi.org/10.24245/mim.v35i3.2306.

OBJECTIVE:

To demonstrate if neutrophil/lymphocyte index predicts mortality in patients with influenza-like pneumonia.

MATERIAL AND METHOD:

A case-control, observational, analytical, cross-sectional, retrospective and retrolective study with patients with influenza like pneumonia who developed severe acute pneumonia from 2009 to 2017. APACHE II, SMART COP and neutrophil lymphocyte index (INL) were calculated. Survival was determined by Kaplan and Meier, for the association between INL and mortality, APACHE II, SMART COP and comorbidities was used χ2 and odds ratio (OR), as well as correlation between APACHE II, SMART COP and INL.

RESULTS:

There were included 69 patients. OR between the INL and mortality was of 0.174 (p = 0.533, IC95% 0.274-2.08). There was significant association between INL and components of the metabolic syndrome in living patients. There was no difference in survival between INL greater or less than 7. Positive correlation between APACHE II and INL of 0.4295 (p = 0.0002, IC95% 0.00 to 0.063).

CONCLUSIONS:

There is an association between INL and metabolic syndrome in liv- ing patients, as well as a positive correlation with APACHE II. There is no association between INL and mortality. The cutoff point of the INL shifted 4 points compared to other populations.

Keywords : Neutrophil; Lymphocyte; Influenza; Pneumonia; Metabolic syndrome; APACHE II.

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