Abstract

HERNANDEZ-MARTINEZ, Alejandro et al. Leukemia of acute presentation and the new therapeutic alternatives. Med. interna Méx. [online]. 2019, vol.35, n.4, pp.553-563.  Epub Mar 26, 2021. ISSN 0186-4866.  https://doi.org/10.24245/mim.v35i4.2548.

Leukemia is a part of a lot of hematologic malignancies that affect leukocyte differentiation in the bone marrow. This illness can be classified according to morphologic, cytochemical and immunological characteristics expressed by blast cells. Clinical manifestations, such as: anemia, thrombocytopenia, bone pains, bleeding, infectious processes, hepatosplenomegaly, among others, are a consequence of blast cell infiltration processes in the bone marrow. Leukemia comprises a heterogeneous group of malignancies that represent a diagnostic and therapeutic challenge, which in the long term generates a biospsycosocial impact on families and patients.

Keywords : Hematologic malignancies; Leukemia; Biphenotypic.