SciELO - Scientific Electronic Library Online

 
vol.35 issue5Deficiency of vitamin D in elderly adults with hip fracture author indexsubject indexsearch form
Home Pagealphabetic serial listing  

Services on Demand

Journal

Article

Indicators

Related links

  • Have no similar articlesSimilars in SciELO

Share


Medicina interna de México

Print version ISSN 0186-4866

Abstract

VERGARA-ORDUNA, Fernando Iván et al. Post- and pre-Valsalva pulse pressure gradient as a marker of left ventricle systolic dysfunction. Med. interna Méx. [online]. 2019, vol.35, n.5, pp.659-668.  Epub Apr 30, 2021. ISSN 0186-4866.  https://doi.org/10.24245/mim.v35i5.2206.

BACKGROUND:

Heart failure affects to 26 million people worldwide. The variation of the blood pressure and heart rate values after performing the Valsalva maneuver has been evaluated, finding a correlation between left ventricular function and natriuretic atrial peptide.

OBJECTIVE:

To determine if post- and pre-Valsalva pulse pressure gradient is useful as marker of left ventricle systolic dysfunction.

MATERIAL AND METHOD:

A cohort study was done from January 1st to June 30, 2017, determining left ventricular ejection fraction, cerebral natriuretic peptide, as well as the subtraction of post-Valsalva and pre-Valsalva pulse pressure, this variable was determined as pulse pressure gradient.

RESULTS:

There were included 32 patients. A gradient figure of less than 4.22 had a negative correlation with a left ventricular ejection fraction lesser than 50%, with a correlation coefficient of -0.562 and a p value of 0.001, in addition to having an area under the curve of 0.71.

CONCLUSIONS:

The gradient and the ejection fraction had a negative correlation, this in the indeterminate area of the systolic function. An LVEF lesser than 50% implies risk of decompensation and a depressed LVEF.

Keywords : Heart failure; Valsalva maneuver; Left ventricular function; Cerebral natriuretic peptide; Pulse pressure.

        · abstract in Spanish     · text in Spanish