Abstract

SANCHEZ MENDOZA, Mariano; VAZQUEZ SANCHEZ, Adrián; GARCIA MANRIQUE, Consuelo  and  AVILA-ZARRAGA, José Gustavo. Reduction of nitro compounds using the Pd/H₂N-NH₂/Mw system. Educ. quím [online]. 2013, vol.24, n.3, pp.347-350. ISSN 0187-893X.

The reduction of nitro compounds to obtain the corresponding amines is one of the most useful reactions in organic synthesis. Of the various methods for achieving such reductions, those based on the transfer of atoms using Hydrogen donors have several advantages over catalytic hydrogenation or reductions via metal/acidic medium, especially due to low complexity involved in experimental development, and in addition to low toxicity of the products. In addition to this and taking the precepts of green chemistry, it is preferred the production of new compounds preventing the generation of hazardous wastes and minimizing the impact on health and the environment. Thus, the goal of this paper is to provide an alternative process for the reduction of nitro compounds by using: a) the Pd/H₂N-NH₂ system in very easy conditions, and b) alternative heating such as microwave energy, with good yields and very short reaction periods.

Keywords : nitro compounds; reduction; amines; catalyst; microwaves.