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Ginecología y obstetricia de México
Print version ISSN 0300-9041
Abstract
KABLY-AMBE, A; CARBALLO-MONDRAGON, E; DURAN-MONTERROSAS, L and ROQUE-SANCHEZ, AM. Recombinant FSH versus recombinant FSH + LH during GnRH antagonist ovarian stimulation for in vitro fertilization. Ginecol. obstet. Méx. [online]. 2017, vol.85, n.11, pp.727-734. ISSN 0300-9041. https://doi.org/10.24245/gom.v85i10.1187.
OBJECTIVE:
To evaluate the effect of adding recombinant LH to IVF GnRH cycles compared to recombinant FSH stimulated cycles.
MATERIALS AND METHODS:
A retrospective, observational, cross-sectional study of 486 cycles of in vitro fertilization was done in the Centro Mexicano de Fertilidad of CEPAM (Hospital Angeles Lomas). We included 529 cases where it was used a stimulation protocol GnRH antagonist flexible scheme and analyzed depending on the utilized gonadotropin scheme.
RESULTS:
529 cycles were studied in which the follicular development and the number of oocytes were higher in the group stimulated with FSHr alone. However, the percentage of oocytes in metaphase II was higher in the group with LHr. The pregnancy rate was higher in the group stimulated with LHr.
CONCLUSION:
There is a benefit of adding rLH to IVF GnRH antagonist stimulation protocols resulting in higher pregnancy rates.
Keywords : In vitro fertilization; recombinant LH; pregnancy rate.
