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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

MARTINEZ-GAYTAN, V et al. Use of Floseal® hemostatic matrix in the management of obstetric hemorrhage: A follow-up and costs related to treatment. Ginecol. obstet. Méx. [online]. 2018, vol.86, n.2, pp.127-136. ISSN 0300-9041.  https://doi.org/10.24245/gom.v86i2.1883.

OBJECTIVE

To evaluate the clinical outcomes and direct costs related to treatment of placenta previa with Floseal® hemostatic matrix as part of the treatment of obstetric hemorrhage in comparison with conventional management only.

METHODS

Clinical records of patients with hemorrhagic hemorrhage, with more than 20 weeks of pregnancy and placenta previa were reviewed, all patients were adults and treated within September and November of 2012 in the “Unidad Médica de Alta Especialidad 23” of the Mexican Institute of Social Security, Monterrey, México. Costs where estimated using the Diario Oficial de la Federación 2013) and a resampling was performed. Clinical and costs outcomes where compared with parametric and non-parametric tests.

RESULTS

29 clinical records (15: Adjuvant Floseal®, 14: conventional treatment only). Floseal® group resulted in less re-interventions (0% vs 57.1%, p 0.0010), days of hospital stay [2(2-4) vs 6(4-11), p 0.0048] and days in the intensive care unit (2.4 ± 1.5 vs 4.5 ± 2.1, p 0.0048). Average cost by resampling was $109,172.00 [CI95% (80,153.10-139,073.71 mexican pesos)] for Floseal® vs 224,289.00 mexican pesos [IC95% (181,881.48-269,061.23)] for conventional treatment at the expense greater number of pieces of Tisseel®, cryoprecipitate, crystalloids and surgical removal of compresses.

CONCLUSIONS

The adjuvant use of Floseal® was associated with fewer re-interventions, days of hospital stay and intensive care. Lower average and total costs associated with treatment were also estimated. Future long-term analyzes and larger sample sizes are necessary to corroborate these results in the Mexican population.

Keywords : Pregnancy and placenta previa; Floseal®; Obstetric Hemorrhage; Crystalloids; Hemostatic.

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