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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

VAZQUEZ-RODRIGUEZ, Juan Gustavo  and  ALBA-GONZALEZ, Ana Victoria De. Morbimortality and perinatal result in patients with pulmonary arterial hypertension. Ginecol. obstet. Méx. [online]. 2018, vol.86, n.8, pp.510-518. ISSN 0300-9041.  https://doi.org/10.24245/gom.v86i8.1826.

Objective:

To determine morbimortality and perinatal result in pregnant patients with pulmonary arterial hypertension attended in an Intensive Care Unit of a third-level medical center.

Materials and method:

Observational, retrospective, cross -sectional and descriptive study including 12 pregnant patients with pulmonary arterial hypertension treated in Intensive Care Unit from 2013- 2016. Morbidity, mortality and perinatal outcome were studied using a review of medical records. For statistical analysis, descriptive statistics (mean, median, standard deviation, range) with SPSS 17 program were used.

Results:

We studied 12 patients of 27.2 ± 7.2 years, with a history of two births, gestational age of 35.5 ± 6.4 weeks; time elapsed from admission to hospital to delivery care 3.8 ± 0.7 days with a stay in the intensive care unit of 1.7 ± 1.2 days. Pregnancy was interrupted, due to acute deterioration of maternal functional class, in 5/12 cases, 10/12 cases were completed in caesarean section. Anesthesia with epidural block was applied to 10/12 and 2/12 patients died. Twelve newborns with prematurity were obtained; of these, 6/12 required critical care and 1 died. The mean pulmonary arterial hypertension was 60.5 ± 18.0 mmHg, and Eisenmenger's syndrome was diagnosed in 7/12, with predominance of patent ductus arteriosus in 4/12. Sildenafil was used in 2/12, cardiovascular drugs in 3/12 and mechanical ventilation in 3/12.

Conclusion:

Morbidity was high but not maternal-fetal mortality, probably due to the effect of treatment in Intensive Care Unit.

Keywords : Pulmonary arterial hypertension; Pregnant; Intensive Care Unit; Maternal fetal mortality.

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