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Ginecología y obstetricia de México
Print version ISSN 0300-9041
Abstract
SANCHEZ-ARANDA, Alejandro et al. Value of the antral follicular count as a predictor of success in in vitro fertilization cycles. Ginecol. obstet. Méx. [online]. 2018, vol.86, n.12, pp.769-778. Epub Sep 30, 2020. ISSN 0300-9041. https://doi.org/10.24245/gom.v86i12.2400.
BACKGROUND:
The association between ovarian reserve test and ovarian response is well established, however, its ability to predict clinical pregnancy and the live birth is limited.
OBJETIVE:
Evaluate the clinical usefulness of the antral follicle count (AFC) to predict clinical pregnancy and live newborn.
MATERIALS AND METHODS:
Retrospective cohort study was made. In fresh IVF cycles, performed at INPer between 2011-2016. Including patients diagnosed with infertility, who underwent in vitro fertilization with fresh embryo transfer. The study variables were age, antral follicle count, basal FSH concentration and number of oocytes captured. A binary logistic regression model was performed. Statistical Package for Social Sciences (SPSS) was used for the statistical analysis. The probability of error alpha <5% was considered significant.
RESULTS:
A total of 923 in vitro fertilization cycles were included. The antral follicle count has a prediction for clinical pregnancy (ABC 0.59) and live birth (ABC 0.57). The optimal cut-off value with the highest percentage of clinical pregnancy (9%) and live birth (10.4%) was presented with a CFA ≥ 8. A higher pregnancy rate is reported when there is a follicular count above ≥8 follicles.
CONCLUSIONS:
It is expected the highest number of clinical pregnancy and live birth when the antral follicle count is for ≥8 follicles.
Keywords : Pregnancy; Pregnancy rate; Ovarian reserve; Live birth; Antral folicle count.