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Ginecología y obstetricia de México
Print version ISSN 0300-9041
Abstract
AGUIRRE-GARCIA, Rosaura et al. Vaginal melanoma. A case report. Ginecol. obstet. Méx. [online]. 2020, vol.88, n.6, pp.402-406. Epub Sep 20, 2021. ISSN 0300-9041. https://doi.org/10.24245/gom.v88i6.3945.
BACKGROUND:
Vaginal melanoma is an exceptional alteration, for which the diagnosis is established in advanced stages of the disease. The short-term prognosis is poor and there are no identified risk factors to date.
CLINICAL CASE:
77-year-old patient, who came to the clinic for fetid transvaginal bleeding, two months old. During colposcopy, a tumor was observed on the left lateral aspect of the vagina, which extended to its lower third; the anterior face was hyperpigmented and friable. Based on the cytology report and biopsy, the diagnosis of invasive melanoma was established. The concentration of tumor markers was positive for HMB-45, Ki 67 (20%), MART-1 (Melan-1) and PS-100. The patient was sent to the Oncology service for staging and treatment of the disease.
CONCLUSIONS:
The identification of a hyperpigmented tumor on gynecological examination, in addition to a directed biopsy, complemented by an immunohistochemical study, is suggestive of vaginal melanoma. Patients with this type of injury should be cared for by a multidisciplinary medical team.
Keywords : Vaginal melanoma; Risk factors; Colposcopy; Invasive melanoma; Tumor markers; Ki-67 biomarker; biopsy; Gynecological examination.