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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

MENDEZ-MIGUEZ, Iria et al. Analysis of endometrial cancer in a university hospital in Ourense, Spain. Ginecol. obstet. Méx. [online]. 2022, vol.90, n.10, pp.819-825.  Epub Jan 27, 2023. ISSN 0300-9041.  https://doi.org/10.24245/gom.v90i10.5296.

OBJECTIVE:

To retrospectively describe the behavior of endometrial cancer in patients diagnosed at the Complexo Hospitalario Universitario de Ourense.

MATERIALS AND METHODS:

Descriptive, observational and retrospective study in the Complexo Hospitalario Universitario de Ourense between September 2014 and January 2018. Inclusion criteria: diagnosis, treatment and follow-up in our center. Exclusion criteria: incomplete history and diagnosis or management in another center. Patient, tumor and treatment variables were collected. A descriptive analysis was performed. Possible associations were tested by Chi-square, Fisher, Student’s t-test and Mann-Whitney test.

RESULTS:

149 patients were studied, with mean age at diagnosis of 69.38 years ± 9.6 years. 86.6% (n = 129) of the patients were postmenopausal. 68% (n = 101) were obese and 54.7% (n = 81) hypertensive. 54.7% (n = 81) were diagnosed at stage IA. 68.4% of grade 3 tumors had myometrial infiltration greater than 50%, 28.6% grade 1 (p < 0.001). Of the patients who received radiotherapy or brachytherapy 46% were advanced stage; 76% stage IB, 26% stage IA (p < 0.001). 91.3% of stage I tumors were type I, in advanced stages there were 48.6% of type I tumors (p < 0.001). 87.4% of grade 1 or 2 tumors were stage I, 45.2% of grade 3 tumors were stage I (p < 0.001).

CONCLUSIONS:

Most patients were older than 60 years and were diabetic, hypertensive and obese. Endometrial cancer is usually diagnosed at early stages. Brachytherapy is the most indicated adjuvant.

Keywords : Endometrial cancer; Postmenopause; Endometrial neoplasms; Brachytherapy; Diabetes mellitus; Obesity.

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