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Ginecología y obstetricia de México

Print version ISSN 0300-9041

Abstract

GALVAN LUNA, Adriana  and  RIVAS LOPEZ, Radamés. Rhabdomyolysis associated with hypokalemia in pregnancy and perinatal aspects. A case report. Ginecol. obstet. Méx. [online]. 2023, vol.91, n.11, pp.840-846.  Epub Mar 08, 2024. ISSN 0300-9041.  https://doi.org/10.24245/gom.v91i11.8844.

BACKGROUND:

Rhabdomyolysis is a syndrome, caused by injury to the muscle fiber, which produces the release of intracellular components such as myoglobin, creatine kinase, aldolase and lactate dehydrogenase, electrolytes, into the extracellular space and blood circulation, which can cause serious complications. such as cardiovascular disorders, cerebral edema and death. There are few reported cases of rhabdomyolysis in pregnancy, the reports described in the literature have been associated with infections and hydroelectrolytic changes. The clinical case is presented due to the importance of the repercussion to the maternal-fetal binomial, since it can result in a serious outcome.

CLINICAL CASE:

The case of a primiparous pregnant patient is presented, who debuted with clinical symptoms accompanied by muscular alterations after an infection, in week 18 of gestation, for which a study protocol was requested with the finding of hydroelectrolyte imbalance, of the hypokalemia type, with sudden elevation of creatine phosphokinase. A positive urine culture for Escherichia coli was found. Management with hydroelectrolyte replacement was indicated, with potassium replacement adjusted to requirements, antibiotic, and nutritional contribution, with hospital discharge after 2 days. Prenatal control was continued and at week 32.2 she presented preeclampsia, which is why a cesarean section was decided, a male weighing 2395 g, Apgar 9/9, with satisfactory evolution of the binomial was obtained.

CONCLUSIONS:

Pregnancy is more susceptible to infections or complications associated with hydroelectrolyte imbalances, rhabdomyolysis can occur in pregnancy, and it is important not to rule it out, its diagnosis can be made clinically and through laboratory tests.

Keywords : Rhabdomyolysis; Pregnancy; Hypokalemia; Electrolyte imbalance.

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