Abstract

MADRIZ-GODOY, María Mayela; SANCHEZ-HERNANDEZ, Eloy  and  ORTIZ-HERNANDEZ, Enrique Gerardo. Sedoanalgesia in neonate based on remifentanyl. In relation to a case for epiglottopexy. Rev. mex. anestesiol. [online]. 2020, vol.43, n.1, pp.64-68.  Epub Sep 27, 2021. ISSN 0484-7903.  https://doi.org/10.35366/cma201l.

The neonatal stage comprises from the first day of birth until day 28 of life. It is characterized by being a stage of anatomical, physiological and metabolic immaturity. Due to these characteristics of neonates, anesthetic drugs have an important impact on their respiratory and cardiovascular physiology, and their immaturity on pharmacokinetics. Laryngomalacia is one of the main causes of stridor in this stage, which depending on its severity could require surgical treatment, such as an epiglotopexy. This procedure requires potent analgesia and at the same time the possibility of maintaining spontaneous ventilation for its appropriate evaluation. This can be achieved with the use of remifentanyl. We present the clinical case of a term neonate of 22 days of age who we administered Remifentanyl as the basis of sedoanalgesia for the successful completion of an epiglotopexy. Its analgesic potency, ability to maintain ventilatory automatism and predictable pharmacokinetics in the neonate, makes it an ideal agent to provide adecuate sedoanalgesia for different procedures with an easy titration profile and rapid recovery in the neonate.

Keywords : Remifentanyl; neonate; newborn; epiglottopexy; sedoanalgesia; anesthesia.

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