Abstract

CAO, Roberto; PEREZ, Lázaro G.; MOYA, Reynaldo  and  DIAZ, Alicia. Interaction of Copper(II) Dithiocarbamates with Hydrogen Peroxide. Rev. Soc. Quím. Méx [online]. 2000, vol.44, n.2, pp.158-162. ISSN 0583-7693.

The possible reaction of copper(II) dithiocarbamates with SOD-like activity and the ligands themselves with hydrogen peroxide was studied. Three dithiocarbamates (DTC) were selected: morpholyl (MorDTC) and those of L-glutamic acid (GluDTC) and L-proline (ProDTC). DTC salts reacted with H₂O₂, in a non-catalytic way, to form the corresponding disulfide and water. It was assumed that a sulfidyl radical is formed as intermediate. When these DTC form highly stable complexes with Cu(II), no interaction takes place. In the case of Cu(GluDTC)₂⁴⁻ a partial dissociation of the complex provokes the reaction of the liberated ligand with H₂O₂, but disulfide is not formed, since apparently the intermediate reacts via redox with Cu(II), conducting to the total decomposition of the complex.

Keywords : copper(II) dithiocarbamates; hydrogen peroxide; redox; complex; decomposition.

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