Abstract

CUEVAS YANEZ, Erick et al. Synthesis of Miconazole and Analogs Through a Carbenoid Intermediate. Rev. Soc. Quím. Méx [online]. 2004, vol.48, n.1, pp.49-52. ISSN 0583-7693.

An alternative synthesis for the preparation of miconazole, enilconazole and econazole is described. The process involves the intermolecular insertion of a carbenoid species to imidazole from α-diazoketones with copper acetylacetonate as the key reaction of the synthesis route.

Keywords : Imidazole; carbenoid; miconazole.