Abstract

CERDA CORTAZA, Luis Juan  and  LOPEZ REYNA, Marco Antonio. Results of preoperative resuscitation in severe sepsis and septic shock in patients with intra-abdominal infections. Cir. gen [online]. 2014, vol.36, n.4, pp.199-204. ISSN 1405-0099.

Introduction: Intra-abdominal infection is characterized by its high incidence and mortality. Mortality rates reported in the literature vary widely and there are no studies that show differences depending on the degree of sepsis present. This study presents only patients with severe sepsis and septic shock of abdominal origin and the impact on mortality by performing preoperative resuscitation using the Surviving Sepsis Campaign guidelines as the only variable that changes the mortality rate.

Material and Methods: A retrospective, observational, analytical and cross-sectional study was conducted in a population of 146 patients with intra-abdominal infection categorized with severe sepsis and septic shock in Tampico General Hospital. Preoperative resuscitation was performed on all patients based on the Surviving Sepsis Campaign guidelines. This was classifi ed as a success or failure, and the impact on mortality was reviewed.

Results: Of the 146 patients, 112 had severe sepsis and 34 septic shock. Resuscitation was considered successful in 105 patients. The overall mortality in the study was 20.5%, with 9.8% for severe sepsis and 55.8% for septic shock. In patients with successful resuscitation, overall mortality decreased to 9.5%, and in patients with severe sepsis it was 2.2% and with septic shock it was 47%, which was statistically signifi cant. (Pearson Chisquare 33, P=.001 and OR 38, 95% CI: 7-208).

Conclusions: The results of the successful preoperative resuscitation in severe sepsis and septic shock in patients with intra-abdominal infection show a statistically significant impact on reducing mortality.

Keywords : Infection; Intra-abdominal; Preoperative resuscitation; Sepsis.