Introduction:

The prevalence of gastric cancer in Mexico has increased in recent years, with a predominance in men. The risk factors are alcohol, tobacco and Helicobacter pylori infection, considering in our population as of moderate risk. Although adenocarcinoma continues to predominate as the most frequent gastric malignancy, a non-negligible percentage of 7-8% according to WHO is occupied by non-Hodgkin’s lymphoma (extranodal) and leiomyosarcomas. The appropriate diagnostic approach and differentiation is crucial between adenocarcinoma and lymphoma, since this depends on prognosis and treatment.

Case report:

A case of a 79 year old man with asthenia, malignant hypercalcemia with an incidental finding of gastric thickening by tomography, in which endoscopic ultrasound was performed for the diagnosis of gastric lymphoma of diffuse variety (Ann Arbor modified II2).

Literature review:

Endoscopic ultrasound is considered a tool for the diagnosis of gastric carcinoma in all its variants, mainly where the disease is in deep layers.

Conclusion:

Endoscopic ultrasound is the method that leads us to obtain high diagnostic accuracy in gastric lymphoma allowing the biopsies of total wall thickness for the cell block to perform differential diagnosis always with immunohistochemistry.

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