Abstract

CERON-ROJAS, J. Jesús  and  SAHAGUN-CASTELLANOS, Jaime. Estimating QTL biometrics parameters in F ₂ populations: a new approach. Agrociencia [online]. 2007, vol.41, n.1, pp.57-73. ISSN 2521-9766.

The standard procedures for constructing maps of Quantitative Trait Loci (QTL) are based on the estimation by maximum likelihood or minimum squares of the QTL biometrics parameters and generally require numerical methods and special software, given that they do not produce explicit estimators. The objective of the present study was to derive explicit estimators of the biometrics parameters of a QTL in an F2 population. The derivation was based on three linear combinations of random variables with mixed normal distribution and a molecular marker. For each linear combination, its mean and variance were determined, with which estimators were derived of the additive effect and dominance effect of the QTL, as well as the frequency of recombination between the QTL and the marker. The explicit estimators obtained here were asyntotically consistent and unbiased, and do not require special software for their evaluation.

Keywords : Quantitative traits; mixed distributions; recombination frequency; molecular markers; likelihood profile.

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