Abstract

PENA-VAZQUEZ, Omar et al. Polymorphisms of ACTN3 and ACE and their relation with athletic performance in individual sports: A systematic review. TIP [online]. 2022, vol.25, e480.  Epub June 23, 2023. ISSN 1405-888X.  https://doi.org/10.22201/fesz.23958723e.2022.480.

Polymorphisms of the ACTN3 and ACE genes related to athletic performance are controversial due to those who favor differences between ethnicity and athletic status. However, although the above is the subject of debate through genetics, it is known that the potential benefits of the R + I allele fall on anaerobic performance and the carriers of the X + D allele on aerobic performance, biologically indicative that the genotype RX + DD + II is the key to the excellent performance of athletes with similar physical abilities and makes both power and endurance phenotypes important. The objective of this paper was to select and describe the studies that support the association of the genotype of the ACTN3 and ACE genes with the performance of individual sports athletes, considered elite for their high sports performance. 1,153 articles on the subject were reviewed and only 13 were included in the research. The results obtained indicate that athletes with the RR/RX + ID/DD genotype stand out in speed/power and those with the XX + II genotype in endurance. In conclusion, it is possible that there is a specific genetic structure associated with the polymorphisms of the ACTN3 and ACE genes that allow them to be predisposed to a high level of anaerobic and/or aerobic performance.

Keywords : Alpha-actinin 3; Physical abilities; Sports efficiency; Angiotensin-converting enzyme; Genotype.

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