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Archivos de cardiología de México
On-line version ISSN 1665-1731Print version ISSN 1405-9940
Abstract
GARCIA-GUTIERREZ, Juan C. et al. Experience with the use of the bio-active stent coated with titanium nitric oxide compared with zotarolimus-eluting stent: experience of a unit medical high specialty. Arch. Cardiol. Méx. [online]. 2016, vol.86, n.1, pp.18-25. ISSN 1665-1731. https://doi.org/10.1016/j.acmx.2015.06.001.
The use of coronary stents in coronary angioplasty has evolved dramatically in its design, type materials, polymers, and a variety of drugs, the use of coronary stents covered nitric oxide have shown satisfactory results in practice, however compared to the results reported drug-eluting stents, there is little information.
Objectives:
The aim of this study was to compare clinical outcomes of a stainless steel stent Bioactive nitric oxide coated titanium (BAS) and a drug-eluting stent zotarolimus (DES) in daily clinical practice.
Methods:
A retrospective, analytical, descriptive and comparative study aimed at evaluating the safety and efficacy of two devices with different characteristics in our population. The primary endpoints were: death, acute infarction (AMI), and re intervention injury Treated (RLT).
Results:
A total of 759 patients were included in the study which was performed angioplasty to a single vessel. Were divided into two arms 382 with DES and 377 patients with BAS, the one year follow up was carried in 95%. After this follow-up period, primary points (cardiovascular death, myocardial infarction, TLR and stent thrombosis) for arm DES vs BAS; 9.5% vs 8.5% P = NS but with shorter periods of dual antiplatelet therapy for arm BAS 6.9 ± 4.1 vs 11.1 ± 2.5 months DES P = .0001. The results were independent of the clinical syndrome of presentation.
Conclusions:
After one year of follow no statistically significant difference in major clinical events, there was a trend in favour of BAS vs SM with respect to revascularization of the target lesion without reaching statistical significance.
Keywords : Angioplasty; Drug eluting stent; Stent thrombosis; Bioactive stenting; México.
