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Archivos de cardiología de México
On-line version ISSN 1665-1731Print version ISSN 1405-9940
Abstract
ARROYO-RODRIGUEZ, Cuitlahuac et al. Risk factors for three-vessel coronary artery disease in patients of Northwest Mexico. Arch. Cardiol. Méx. [online]. 2018, vol.88, n.5, pp.423-431. Epub Dec 04, 2020. ISSN 1665-1731. https://doi.org/10.1016/j.acmx.2018.02.009.
Introduction:
Three-vessel coronary artery disease is an advanced manifestation of atherosclerosis, with high prevalence in Mexico.
Objective:
The aim of this study was to describe coronary risk factors in a group of patients with three-vessel coronary artery disease in Northwest Mexico.
Methods:
A cross sectional study was conducted on a population with three-vessel coronary artery disease from May 2015 to February 2016. The disease was defined when ≥70% stenosis was present in each major epicardial coronary artery. Anthropometric and biochemical parameters were measured in each patient. Ankle-Brachial Index was measured with vascular ultrasound, and Syntax score calculation with an on-line application. Statistical analysis for qualitative differences was performed using Pearson X2 test, with p < 0.05 being considered as significant.
Results:
The study included 100 patients, of whom 75 were male (mean age 63 ± 9 years) and 25 female (mean age 69 ± 9 years). The coronary risk factors observed were diabetes (58%), hypertension (86%), smoking (68%), dyslipidaemia (100%), metabolic syndrome (71%), and obesity/overweight (75%). Diabetes and metabolic syndrome prevalence was higher in women (p = 0.03), but smoking was higher in men (76%, p = 0.003). Ankle-Brachial Index was abnormal in 58% of patients, the mean Syntax score was in 36.9 ± 11.5, and the prevalence of left main coronary heart disease was 36%.
Conclusions:
This group of patients with complex coronary lesions has a high prevalence of coronary risk factors, which could represent a worse prognosis.
Keywords : Coronary artery disease; Atherosclerosis; Risk factors; Syntax score; Ankle-Brachial Index; Mexico.