Abstract

HERRERA-SILVA, Jorge Carlos; TREVINO-MOORE, Aida  and  MEDINA-ROSALES, Hilda. Association between low-grade inflammation markers and body mass index in children with cancer undergoing chemotherapy. Bol. Med. Hosp. Infant. Mex. [online]. 2008, vol.65, n.3, pp.167-178. ISSN 1665-1146.

Introduction. Systemic inflammation markers and cancer have been associated over the last years. Objectives: To estimate and to know the degree of association between body mass index (BMI) and markers of low-grade systemic inflammation in children with cancer. Methods. Medical histories were reviewed, and body measurements were made in a series of cases. Anthropometric variables and biochemical markers of systemic inflammation were analyzed. Non-parametric statistics was applied to data. Results. Twenty-five patients participated. No association between BMI and markers of low-grade systemic inflammation was found. Global prevalence of the inflammatory syndrome was 72%. Fibrinogen showed moderate correlation with C reactive protein (r =0.500) in both, solid and hematologic neoplasms (r =0.621), and with VSG only in the hematologic ones (r =0.605). Conclusions. No association between markers of systemic inflammation and BMI was found in this study. The prevalence of the inflammatory syndrome is very high.

Keywords : Systemic inflammatory syndrome; chemotherapy; pediatrics; cancer; body mass index.

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