Abstract

HERNANDEZ HERRERA, Ricardo; FLORES SANTOS, Roberto; MARTINEZ-MARRUFO, Ana María  and  CHAVEZ-CRUZ, Olga. Intrauterine growth retardation in a 480 g neonate at birth. Bol. Med. Hosp. Infant. Mex. [online]. 2010, vol.67, n.5, pp.444-448. ISSN 1665-1146.

Background. There are few cases of live neonates with intrauterine growth retardation (IGR) <500 g with a satisfactory outcome, including apparent normal neurodevelopment. Clinical case. We report the case of a female 480 g neonate diagnosed with severe IGR who was the product of a 30-year-old mother. This was the first gestation and delivery was at 31 gestation weeks. The neonate demonstrated severe oligoamnios and was delivered by Cesarean section. Apgar score was 7-7, oxygen was administered at 48 h, and parenteral nutrition and formula for premature infants was initiated. Serum cytomegalovirus IgG and IgM and cytomegalic urine inclusion were all negative. The infant accepted formula and was asymptomatic. She reached 500 g at 20 days of life. At 5 months old, her weight increased to 1 700 g before hospital discharge. Patient was followed-up until 1 year of age. She weighed 2.8 kg and demonstrated a 6-month delay in psychomotor neurodevelopment. It is important to mention that she did not develop retinopathy of prematurity, periventricular leukomalacia or intracranial hemorrhage. Conclusion. The patient presented here was born after 31 weeks gestation with a birth weight of 480 g. She showed severe IGR with neurodevelopmental delay; however, no retinopathy of prematurity, periventricular leukomalacia or intracranial hemorrage was demonstrated.

Keywords : severe growth intrauterine retardation; 480 g neonate.