Abstract

LOPEZ VALDEZ, Jaime Asael; CASTRO COYOTL, Dulce María  and  VENEGAS VEGA, Carlos Alberto. New embryological hypothesis, genetics and epidemiology of gastroschisis. Bol. Med. Hosp. Infant. Mex. [online]. 2011, vol.68, n.3, pp.245-252. ISSN 1665-1146.

Gastroschisis is defined as an abdominal wall malformation characterized by visceral herniation with an intact umbilical cord and absence of membrane. At present, six theories to explain the embryogenesis of this entity have been proposed. Although its etiology remains unknown, it is recognized with a multifactorial inheritance pattern. Recently, an increase of cases worldwide has been observed, particularly in Mexico. For that reason, some authors suggest this entity is pandemic. We performed an updated review of the abdominal wall embryology, theories, epidemiology and genetic-environmental risk factors involved in the development of gastroschisis.

Keywords : gastroschisis; theories; genetic-environmental factors.