Abstract

MARQUEZ-GONZALEZ, Horacio; IBARRA RIOS, Daniel; JEAN TRON, María G.  and  BARAJAS-NAVA, Leticia A.. Use of sildenafil for pulmonary hypertension in neonates. Bol. Med. Hosp. Infant. Mex. [online]. 2020, vol.77, n.4, pp.202-206.  Epub Sep 29, 2020. ISSN 1665-1146.  https://doi.org/10.24875/bmhim.20000041.

Pulmonary arterial hypertension is a multifactorial nosological entity that increases neonatal mortality as a result of heart failure. Pulmonary vasodilators are the cornerstone of treatment, of which sildenafil is the most commonly used drug. Therefore, the results of a recently updated Cochrane systematic review are summarized, in which the efficacy and safety of sildenafil for the treatment of pulmonary hypertension in neonates was evaluated.

Keywords : Newborn; Pulmonary arterial hypertension; Sildenafil; Mortality; Systematic review.