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Boletín médico del Hospital Infantil de México
Print version ISSN 1665-1146
Abstract
DOMINGUEZ-ROJAS, Jesús et al. Hyperferritinemic sepsis secondary to invasive Toxoplasma gondii in a child with untreated HIV. Bol. Med. Hosp. Infant. Mex. [online]. 2023, vol.80, suppl.1, pp.7-11. Epub Sep 11, 2023. ISSN 1665-1146. https://doi.org/10.24875/bmhim.22000051.
Background:
Untreated human immunodeficiency virus (HIV)-immunosuppressed pediatric patients show high morbidity and mortality from opportunistic infections. Limited cases of hyperferritinemic sepsis have been described in patients with toxoplasmosis.
Case report:
We describe the case of a 13-year-old female patient with a history of untreated HIV who presented with hyperferritinemic sepsis secondary to Toxoplasma gondii infection and Pneumocystis jirovecci pneumonia. She received ventilatory support, inotropic drugs, treatment for opportunistic germs, and high-dose corticosteroids, but with unfavorable evolution.
Conclusions:
The global approach to sepsis with elevated ferritin guides to using of therapies aimed at neutralizing the severe inflammatory response. A timely diagnosis would allow prompt treatment and minimize complications.
Keywords : Sepsis; Ferritin; Lymphohistiocytosis; Hemophagocytic.Child; Human immunodeficiency virus.
