Abstract

GALLEGOS, I. Belem et al. El Papel de la Galectina-3 en el desarrollo del cancer de mama. Rev. educ. bioquím [online]. 2013, vol.32, n.1, pp.03-12. ISSN 1665-1995.

Breast cancer is the second cause of death of women in the world and when it is diagnosed opportunely can be cured. Recently it has been observed that changes in the oligosaccharides structures of membrane proteins are related to the transformation processes and cellular proliferation, in addition, the presence of receptor for these carbohydrates, can potentialise the metastatic capacity of the tumor. In this revision a general overview of the glycosylated markers and their receptors, especially galectin-3 that, has been associated to the breast cancer.

Keywords : Carbohydrates; breast cancer; lectins; galectin-3.