Abstract

DOUDA, J. et al. Marcadores Cuánticos para la Detección de Cáncer: Revisión. Superf. vacío [online]. 2008, vol.21, n.4, pp.10-15. ISSN 1665-3521.

The current state of knowledge in the field of quantum dots and the perspective for QD applications for early cancer diagnostic are presented. Different methods of synthesize core-shell particles, their polymer encapsulation and the conjugation of QDs with biomolecules are discussed as well. Methods of optical study of QDs with and without conjugation to biomolecules are presented and discussed together with some experimental results of Raman Spectroscopy and photoluminicence studies in these QDs. Finally, it is proposed a methodology for the preparation of hybrids based on the quantum dots with cancer antibodies and the analysis of their optical properties for early cancer diagnostics.

Keywords : Quantum dots; Antibodies; Antigens; Cancer; Nanoparticles; Polymers.