Abstract

PEREZ SOLANO, R.; GUTIERREZ JUAREZ, G.  and  POLO-PARADA, L.. Modelo esféricamente simétrico de la señal fotoacústica en el dominio temporal producida por objetos micrométricos: el caso de células de melanoma in vitro. Superf. vacío [online]. 2012, vol.25, n.2, pp.75-81. ISSN 1665-3521.

An analytical solution for the photoacoustic pressure generated by spherically symmetric objects was obtained by considering decay in the absorbed energy density by unit of time in accordance with Lambert - Beer law. Then the solution was expressed in terms of the Kirchhoff equation. Using the resulting equation, and considering that in biological tissues the dominant mechanism is the thermo elastics expansion, we analyze the expected behavior of the photoacoustic pressure generated by melanoma cell in vitro. We compare the photoacoustic signal generated by one, two and a cell monolayer. Finally, we evaluated our analytical results with the experimental obtained previously [1, 2], showing a good qualitative concordance between theory and experiment.

Keywords : photoacoustic; cancer cells; identification; numerical solution; single cell; monolayer.