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Revista mexicana de neurociencia
On-line version ISSN 2604-6180Print version ISSN 1665-5044
Abstract
PARRA MEDINA, Luis E. et al. Clinical and environmental risks factors associated with Parkinson’s disease in Yucatan. Rev. mex. neurocienc. [online]. 2022, vol.23, n.4, pp.130-136. Epub Oct 07, 2022. ISSN 2604-6180. https://doi.org/10.24875/rmn.22000007.
Objective:
The objective of the study is to identify the risk and protective factors associated with Parkinson’s disease (PD) in inhabitants of Yucatan.
Methods:
Case control study. A questionnaire with the main risk and protective factors for PD described in the literature was applied to cases and controls
Results:
The sample consisted of 85 cases and 124 controls. In the univariate logistic regression analyzes, it was found that the following factors were significantly associated with a higher risk of developing pD family history of (OR = 5.28, p = 0.001), personal history of diabetes (OR = 2.35, p = 0.01), the number of head trauma (OR = 1.35, p = 0.02), number of general anesthesia received (OR = 1.27, p = 0.050), exposure to organic solvents (OR = 2.73, p = 0.02) and the years of exposure to organic solvents (OR = 1.05, p = 0.01):
Conclusions:
The findings of this research indicate that the inhabitants of the state of Yucatan are exposed to the following risk factors having a relative with PD, personal history of diabetes, number of head traumas, exposure to organic solvents, years of exposure to organic solvents and number of general anesthesia received.
Keywords : Case-control study; Parkinson’s disease; Risk and protection factors; Head trauma; General anesthesia.