Abstract

CABELLO RUIZ, Ethel Daniela et al. Antimicrobial activity of protein extract of Aloe vera leaves. Rev. mex. cienc. farm [online]. 2015, vol.46, n.1, pp.41-46. ISSN 1870-0195.

Infectious diseases remain a public health problem that is exacerbated by the presence of resistant organisms leading to development of novel drugs. Study of pharmacological proteins from natural sources recently emerged. In this research extraction of proteins from gel of Aloe vera and antimicrobial evaluation were done. Protein extracts from Aloe vera were obtained by two methods: extract 1(EP1) by precipitation with (NH4)2SO4 and (EP2) by phenol extraction. The yield for method 2 (0.33 % recovery). Analysis by mass spectrometry of EP1 identified with a high degree of confidence, peptide 5 and 31-kDa protein, whose identity has been associated with the glycoproteins of Arabidopsis thaliana. EP2 exhibited inhibitory activity against Staphylococcus aureus and Candida albicans. A. vera extract comprises a promising source of protein with anti-S. aureus and anti-C. albicans activity.

Keywords : Aloe vera; protein; antimicrobial activity.

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