Abstract

MOHTAT, Bita et al. Synthesis of Dialkyl 2-(4-oxopyridin-1(4H)-yl)dicarboxylates Through the Reaction of 4-hydroxypyridine and Dialkyl Acetylenedicarboxylate in the Presence of Triphenylphosphine. J. Mex. Chem. Soc [online]. 2011, vol.55, n.3, pp.194-196. ISSN 1870-249X.

4-Hydroxypyridine undergoes a smooth reaction with dialkyl acetylenedicarboxylates in the presence of triphenylphosphine (15 mol %) to produce the E/Z isomers of dialkyl 2-(4-oxopyridin-1(4H)-yl)but-2-enedioates in high yields.

Keywords : 4-Hydroxypyridine; dialkyl acetylenedicarboxylates; triphenylphosphine; dialkyl 2-(4-oxopyridin-1(4H)-yl)but-2-enedioates.