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Revista bio ciencias
On-line version ISSN 2007-3380
Abstract
OLMEDO-JUAREZ, A. et al. Eclosion inhibition of Haemonchus contortus eggs with two extracts of Caesalpinia coriaria fruits. Revista bio ciencias [online]. 2022, vol.9, e1121. Epub Apr 12, 2024. ISSN 2007-3380. https://doi.org/10.15741/revbio.09.e1121.
Haemonchus contortus is a gastrointestinal parasite of small ruminants. The objective of the study was to evaluate the effect of the acetonic and ethanolic extracts of the Caesalpinia coriaria fruits legume on the egg eclosion inhibition (EEI) of H. contortus in small ruminants. For this effect, it was evaluated at different concentrations of the extracts (acetonic: 20.0, 10.0, 5.0, 2.5, 1.2 and 0.6 mg / mL), (ethanolic: 6.15, 3.12, 1.56 and 0.78 mg / mL), and methanol 4 % v/v in distilled water as negative control and ivermectin 0.5 % as positive control, were used. The inhibitory effect data were analyzed with a completely randomized design by analysis of variance using the general linear model and the Tukey test (p <0.05); the lethal concentrations (LC50 and LC90) were estimated by the Probit analysis of the statistical analysis systems (SAS) program. The inhibitory effects of the extracts depended on the concentration, where the inhibitory activity was comparatively similar to the positive control doses of 1.2 mg/mL for the acetonic extract (AE) and 0.78 mg/mL for the ethanolic extract (EE), (p < 0.0001). The LC50 were AE = 0.23 mg/mL and EE = 0.014 mg/mL; LC90 AE = 1.04 mg/mL and EE = 0.14 mg/mL. The results indicate that the EEI of the extracts elaborated with the C. coriaria fruits in acetonic and ethanolic solvent have inhibitory activity against H. contortus eggs eclosion, nevertheless, requires further investigations as antiparasitic for oral use in animals.
Keywords : Caesalpinia coriaria; Haemonchus contortus; parasite; eggs.